How and when to use the thiol conjugation approach: an introductory guide

December 13th, 2016

A traditional method for linking proteins to molecules relies on the formation of a stable covalent bond between thiol (R-SH) and maleimide groups. When these functional groups are positioned on separate biomolecules (A & B) a hybrid conjugate AB (but not AA or BB) will form. Despite other systems of conjugation being available (for instance,…

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InnovaCoat® GOLD nanoparticles reference

New Reference – InnovaCoat® GOLD nanoparticles

December 6th, 2016

Our InnovaCoat® GOLD nanoparticles and conjugation kits have been recently published! Introduction Vitamin B12 is a water-soluble vitamin, necessary for a variety of cellular functions such as DNA synthesis and normal blood formation. Low levels of vitamin B12 are mainly caused by low consumption of meat, fish and dairy products. Commercially available kits for diagnostic…

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InnovaCoat® GOLD

Using InnovaCoat® GOLD in your assay – references

November 28th, 2016

The use of ultra-pure gold nanoparticles such as InnovaCoat® GOLD conjugation kits produces highly stable conjugates that can be used in a variety of scientific applications. Take a look at some of the published research in the table below that has used InnovaCoat® GOLD technology to produce antibody:nanoparticle conjugates for use in a variety of scientific applications……

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New Reference – PiColorLock™

October 27th, 2016

PiColorLock™ has been published in Nature! Tuberculosis (TB) is a major health concern and worldwide emergence of resistant forms of Mycobacterium tuberculosis (Mtb) has further aggravated the situation. As most of the available clinical drugs have single targets in the pathogens, these drugs become ineffective over time due to the development of bacterial resistance against…

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Latex conjugation kit Reference

October 25th, 2016

Our Blue and Red Latex beads have been recently published! Acute undifferentiated febrile illnesses (AFIs) are responsible for substantial morbidity and mortality globally. Today, the most effective treatments for patients affected by AFIs rely on the identification of the causative infectious agents, examples of which include Chikungunya (CHIKV) and Dengue (DENV). The initial diagnosis is…

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Lightning-Link® Rapid Biotin Referenced in Nature

Lightning-Link® Rapid Biotin has been Published in Nature!

October 24th, 2016

Fc Receptors (FcRs) are key molecules for the recognition and elimination of foreign antigens. Among members of this family, FcgRI is expressed on mono myeloid cells, whose crosslink with immune complexes can initiate cellular responses and receptor / ligand internalization. However, while the first event is well described, the cellular processes involving FcgRI / ligand…

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ATP Agarose and ATPase Assay Kit Reference

October 13th, 2016

Our ATP agarose and ATPase assay kit have been published in Nature! In this paper, the authors investigate the role played by the chaperone Hsp70 in protein refolding and degradation; a cellular event triggered under proteotoxic stress-conditions. More specifically, they elucidate how the Hsp70 switch mode of action is mediated by ARD1 acetylation activity, which…

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Gold Nanoparticle Conjugates

Gold Nanoparticle Conjugates Reference

October 7th, 2016

InnovaCoat® GOLD conjugates have been published in Nature! The authors used our InnovaCoat® GOLD goat anti-rabbit IgG gold conjugates to detect LC3 in spermatozoa which had previously been incubated with an anti-LC3 primary antibody. Their study showed that autophagy-related proteins, such as LC-3, are functionally active in spermatozoa, plus they might play a role in…

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Expedeon Introduces the AbPure Magnetic Purification System

September 19th, 2016

Unique antibody purification system compatible with any conjugation technology Cambridge, UK, 19 September 2016: Expedeon (Innova), a specialist provider of bioconjugation products and services, today announced the launch of the AbPure™ Magnetic Purification system. The system is based on Protein A Magnetic Beads, which have a high affinity for IgG molecules and allow scientists to…

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Using Lightning-Link® antibody conjugates for Flow Cytometry

September 12th, 2016

Using Lightning-Link® antibody conjugates for Flow Cytometry – references Directly labeling primary antibodies using Lightning-Link® kits produces conjugates that can be used in a variety of scientific applications. Take a look at some of the published research in the table below that has used Lightning-Link® technology to produce antibody conjugates for use within Flow Cytometry……

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Using Lightning-Link® conjugates for Immunocytochemistry

September 7th, 2016

Using Lightning-Link® conjugates for Immunocytochemistry – references Directly labeling primary antibodies using Lightning-Link® kits produces conjugates that can be used in a variety of scientific applications. Take a look at some of the published research in the table below that has used Lightning-Link® technology to produce conjugates for use within Immunocytochemistry… Title Pubmed ID Label…

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Using Lightning-Link® conjugates for Western Blot

August 19th, 2016

Using Lightning-Link® conjugates for Western blot – references Directly labeling primary antibodies using Lightning-Link® kits produces conjugates that can be used in a variety of scientific applications. Take a look at some of the published research in the table below that has used Lightning-Link® technology to produce conjugates for use within Western Blot… Title Pubmed…

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