InnovaCoat® GOLD nanoparticle
InnovaCoat® GOLD-Carboxyl nanoparticles are coated gold nanoparticles functionalized with carboxyl groups that allow the covalent conjugation of antibodies, using the water-soluble carbodiimide crosslinker EDC.
The product enables the generation of highly stable covalent gold-antibody conjugates at R&D and manufacturing scales.
Unlike traditional EDC/NHS coupling used to activate carboxyl groups, InnovaCoat® GOLD-Carboxyl nanoparticles are optimized for single step EDC covalent coupling without signs of aggregation. This eliminates the need for EDC/NHS pre-activation and washing steps associated with traditional conjugations.
This process is also significantly faster than standard methods, with conjugates ready to use in less than 35 minutes.
InnovaCoat® GOLD carboxyl nanoparticles have a narrow size distribution, a uniform spherical shape and high batch-to-batch consistency.
Mean Diameter 36-44nm
Composition: 40nm carboxyl-gold 40 OD carboxyl gold nanoparticles web
Adsorption max: 530nm
Particles per ml: 36 x 1011
Volume: 1ml and 5ml
Buffer: 10mM EPPS pH 8.5